Stem Cell-Dependent Therapies Book Full Pages Sell

Stem Cell-Dependent Therapies one of the 100 books to read presented by Walter de Gruyter on 2013-10-29 is very recommended for you if you find book about Medical / Biotechnology, Medical / Immunology, Science / Life Sciences / Genetics & Genomics, Science / Life Sciences / Molecular Biology, Science / Life Sciences / Biology, . one of the 100 books to read composed by Gerhard Gross, Thomas Häupl, with count of page 426 Pages. you can see book detail at the bottom

Download Stem Cell-Dependent Therapies Mesenchymal Stem Cells in Chronic Inflammatory Disorders full pages

Stem Cell-Dependent Therapies book cover
ISBN: 9783110298307


Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD).
This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation.


Stem Cell-Dependent Therapies



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