PNH and the GPI-Linked Proteins for a book lover published by Elsevier in the year 2000-04-28 is very recommended for you if you want book about Medical / Hematology, Medical / Oncology, Science / Life Sciences / Biochemistry, Science / Life Sciences / Cell Biology, Science / Life Sciences / Biophysics, . for a book lover composed by Neal S. Young, Joel Moss, with page count 279 Pages. you can found book summary at the bottom
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ISBN: 9780080492094
Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients.
Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins.
This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins.
- Outlines the chemical features of PNH
- Explains the mechanism of hemolysis
- Includes work on the biochemistry of glycophosphoinositol anchors
- Contains descriptions of the chemistry and biophysics of GPI-anchored proteins
PNH and the GPI-Linked Proteins
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